The Meyer and Teruel Labs seek to understand how human cells move, divide, and differentiate in order to build, maintain and repair tissues and organs. The movement, division, and differentiation of cells is controlled by integration of large numbers of receptor, cell contact, and stress signaling inputs that control the maintenance and repair of tissues but can also cause tissue dysfunction and cancer. We explore fundamental cell-specific and general regulatory processes and identify new therapeutic targets by developing cutting edge live-cell microscopy approaches and in vitro cultured and organoid models to study cell movement, proliferation and differentiation. Current projects focus on the role of the actin cortex and polarized signaling in directed migration, the signaling system that regulates proliferation in normal and cancer cells, the role of cellular oscillators in cell differentiation, and the molecular mechanisms underlying adipogenesis. We are actively recruiting Ph.D. students, M.D./Ph.D. students, and postdoctoral fellows.
A fun NY adventure riding ferries and 4-seater bikes with great views of the Statue of Liberty and Manhattan!
Membrane-proximal F-actin restricts local membrane protrusions and directs cell migration
Intravital imaging reveals cell cycle-dependent satellite cell migration during muscle regeneration
Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation
Depts. of Biochemistry and Cell & Developmental Biology
1300 York Avenue, A402-412
NY, NY 10065